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Journal of Biomedical Optics • Open Access

Light forces the pace: optical manipulation for biophotonics
Author(s): David J. Stevenson; Frank J. Gunn-Moore; Kishan Dholakia

Paper Abstract

The biomedical sciences have benefited immensely from photonics technologies in the last 50 years. This includes the application of minute forces that enable the trapping and manipulation of cells and single molecules. In terms of the area of biophotonics, optical manipulation has made a seminal contribution to our understanding of the dynamics of single molecules and the microrheology of cells. Here we present a review of optical manipulation, emphasizing its impact on the areas of single-molecule studies and single-cell biology, and indicating some of the key experiments in the fields.

Paper Details

Date Published: 1 July 2010
PDF: 21 pages
J. Biomed. Opt. 15(4) 041503 doi: 10.1117/1.3475958
Published in: Journal of Biomedical Optics Volume 15, Issue 4
Show Author Affiliations
David J. Stevenson, Univ. of St. Andrews (United Kingdom)
Frank J. Gunn-Moore, Univ. of St. Andrews (United Kingdom)
Kishan Dholakia, Univ. of St. Andrews (United Kingdom)


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