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Journal of Biomedical Optics • Open Access

Computational study of scattering from healthy and diseased red blood cells
Author(s): Özgür Ergül; Ayça Arslan-Ergül; Levent Gürel

Paper Abstract

We present a comparative study of scattering from healthy red blood cells RBCs and diseased RBCs with deformed shapes. Scattering problems involving three-dimensional RBCs are formulated accurately with the electric and magnetic current combined-field integral equation and solved efficiently by the multilevel fast multipole algorithm. We compare scattering cross section values obtained for different RBC shapes and different orientations. In this way, we determine strict guidelines to distinguish deformed RBCs from healthy RBCs and to diagnose various diseases using scattering cross section values. The results may be useful for designing new and improved flow cytometry procedures.

Paper Details

Date Published: 1 July 2010
J. Biomed. Opt. 15(4) 045004 doi: 10.1117/1.3467493
Published in: Journal of Biomedical Optics Volume 15, Issue 4
Show Author Affiliations
Özgür Ergül, Univ. of Strathclyde (United Kingdom)
Ayça Arslan-Ergül, Univ. of Strathclyde (United Kingdom)
Levent Gürel, Bilkent Univ. (Turkey)

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