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Journal of Biomedical Optics • Open Access

Real-time monitoring of cardiac radio-frequency ablation lesion formation using an optical coherence tomography forward-imaging catheter
Author(s): Christine P. Fleming; Hui Wang; Kara J. Quan; Andrew M. Rollins

Paper Abstract

Radio-frequency ablation (rfa) is the standard of care for the treatment of cardiac arrhythmias; however, there are no direct measures of the successful delivery of ablation lesions. Optical coherence tomography (OCT) imaging has the potential to provide real-time monitoring of cardiac rfa therapy, visualizing lesion formation and assessing tissue contact in the presence of blood. A rfa-compatible forward-imaging conical scanning probe is prototyped to meet this need. The forward-imaging probe provides circular scanning, with a 2-mm scan diameter and 30-µm spot size. During the application of rf energy, dynamics are recorded at 20 frames per second with a 40-kHz A-line rate. Real-time monitoring of cardiac rfa lesion formation and imaging in the presence of blood is demonstrated ex vivo in a swine left ventricle with a forward, flexible, circular scanning OCT catheter.

Paper Details

Date Published: 1 May 2010
PDF: 3 pages
J. Biomed. Opt. 15(3) 030516 doi: 10.1117/1.3459134
Published in: Journal of Biomedical Optics Volume 15, Issue 3
Show Author Affiliations
Christine P. Fleming, Case Western Reserve Univ. (United States)
Hui Wang, Case Western Reserve Univ. (United States)
Kara J. Quan, MetroHealth Medical Ctr. (United States)
Andrew M. Rollins, Case Western Reserve Univ. (United States)

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