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Journal of Biomedical Optics

Optical tomography method that accounts for tilted chest wall in breast imaging
Author(s): Yasaman Ardeshirpour; Quing Zhu
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Paper Abstract

The chest wall underneath breast tissue distorts light reflection measurements, especially measurements obtained from distant source-detector pairs. For patients with a chest wall located at a shallower depth, the chest-wall effect needs to be considered in the image reconstruction procedure. Following our previous studies, this work systemically evaluates the performance of a two-layer model-based reconstruction using the finite element method, and compares it with the performance of the semi-infinite model. The results obtained from simulations and phantom experiments show that the two-layer model improves the light quantification of the targets. The improvements are attributed to improved background estimation and more accurate weight matrix calculation using a two-layer model compared to the semi-infinite model. Fitted two-layer background optical properties obtained from a group of ten patients with chest walls located less than 2 cm deep are more representative of breast tissue and chest-wall optical properties.

Paper Details

Date Published: 1 July 2010
PDF: 14 pages
J. Biomed. Opt. 15(4) 041515 doi: 10.1117/1.3449570
Published in: Journal of Biomedical Optics Volume 15, Issue 4
Show Author Affiliations
Yasaman Ardeshirpour, Univ. of Connecticut (United States)
Quing Zhu, Univ. of Connecticut (United States)

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