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Journal of Biomedical Optics • Open Access

Optical microangiography provides depth-resolved images of directional ocular blood perfusion in posterior eye segment
Author(s): Ruikang K. Wang; Lin An; Spencer Saunders; David J. Wilson

Paper Abstract

In this paper, we demonstrate that the optical microangiography (OAMG) is capable of depth-resolved imaging of directional blood perfusion within both retinal and choroid in the posterior segment of human eye. The study uses an OMAG system operating at 840 nm with an imaging speed at 27,000 A-scans per second. Sequentially registered multiple OMAG projection maps of small areas (~1 mm×1 mm) are combined to provide directional blood flow images for a larger field of view. It takes ~3.7 sec to image a small area (1×1 mm2), and ~2.5 min for a larger field (3×3 mm2). Finally, we show superior performance of OMAG in providing functional images of capillary level microcirculation at different depths of retina and choroid that correlate well with the standard retinal pathology.

Paper Details

Date Published: 1 March 2010
PDF: 3 pages
J. Biomed. Opt. 15(2) 020502 doi: 10.1117/1.3353958
Published in: Journal of Biomedical Optics Volume 15, Issue 2
Show Author Affiliations
Ruikang K. Wang, Oregon Health & Science Univ. (United States)
Lin An, Oregon Health & Science Univ. (United States)
Spencer Saunders, Oregon Health & Science Univ. (United States)
David J. Wilson, Oregon Health & Science Univ. (United States)

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