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Journal of Biomedical Optics

Fluorescence diffuse optical tomography for free-space and multifluorophore studies
Author(s): Anne Koenig; Lionel Hervé; Georges Gonon; Véronique Josserand; Michel Berger; Jean-Marc Dinten; Jerome Boutet; Philippe Peltié; Jean-Luc Coll; Philippe Rizo
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Paper Abstract

We present two major advances in preclinical fluorescence-enhanced diffuse optical tomography (fDOT) system and assess its performance. It is now possible to perform experiments without adaptation liquid or a glass plate over the animal, and our system is equipped with a filter wheel in order to discriminate two injected fluorophores. Evaluation carried out on characterization phantoms and in vivo on mice demonstrates enriched use of the system for biological studies on small animals.

Paper Details

Date Published: 1 January 2010
PDF: 8 pages
J. Biomed. Opt. 15(1) 016016 doi: 10.1117/1.3309738
Published in: Journal of Biomedical Optics Volume 15, Issue 1
Show Author Affiliations
Anne Koenig, Commissariat à l'Énergie Atomique (France)
Lionel Hervé, Commissariat à l'Énergie Atomique (France)
Georges Gonon, Commissariat à l'Énergie Atomique (France)
Véronique Josserand, Institut Albert Bonniot (France)
Michel Berger, Commissariat à l'Énergie Atomique (France)
Jean-Marc Dinten, Commissariat à l'Énergie Atomique (France)
Jerome Boutet, Commissariat à l'Énergie Atomique (France)
Philippe Peltié, Commissariat à l'Énergie Atomique (France)
Jean-Luc Coll, Institut Albert Bonniot (France)
Philippe Rizo, Commissariat à l'Énergie Atomique (France)


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