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Journal of Biomedical Optics • Open Access

Integrated intravascular optical coherence tomography ultrasound imaging system
Author(s): Jiechen Yin; Hao-Chung Yang; Xiang Li; Jun Zhang; Qifa Zhou; Chang Hong Hu; K. Kirk Shung; Zhongping Chen

Paper Abstract

We report on a dual-modality optical coherence tomography (OCT) ultrasound (US) system for intravascular imaging. To the best of our knowledge, we have developed the first integrated OCT-US probe that combines OCT optical components with an US transducer. The OCT optical components mainly consist of a single-mode fiber, a gradient index lens for light-beam focusing, and a right-angled prism for reflecting light into biological tissue. A 40-MHz piezoelectric transducer (PZT-5H) side-viewing US transducer was fabricated to obtain the US image. These components were integrated into a single probe, enabling both OCT and US imaging at the same time. In vitro OCT and ultrasound images of a rabbit aorta were obtained using this dual-modality imaging system. This study demonstrates the feasibility of an OCT-US system for intravascular imaging, which is expected to have a prominent impact on early detection and characterization of atherosclerosis.

Paper Details

Date Published: 1 January 2010
PDF: 3 pages
J. Biomed. Opt. 15(1) 010512 doi: 10.1117/1.3308642
Published in: Journal of Biomedical Optics Volume 15, Issue 1
Show Author Affiliations
Jiechen Yin, Univ. of California, Irvine (United States)
Hao-Chung Yang, The Univ. of Southern California (United States)
Xiang Li, The Univ. of Southern California (United States)
Jun Zhang, Beckman Laser Institute and Medical Clinic (United States)
Qifa Zhou, The Univ. of Southern California (United States)
Chang Hong Hu, The Univ. of Southern California (United States)
K. Kirk Shung, The Univ. of Southern California (United States)
Zhongping Chen, Beckman Laser Institute and Medical Clinic (United States)


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