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Journal of Biomedical Optics • Open Access

Doppler variance imaging for three-dimensional retina and choroid angiography

Paper Abstract

We demonstrate the use of Doppler variance (standard deviation) imaging for 3-D in vivo angiography in the human eye. In addition to the regular optical Doppler tomography velocity and structural images, we use the variance of blood flow velocity to map the retina and choroid vessels. Variance imaging is subject to bulk motion artifacts as in phase-resolved Doppler imaging, and a histogram-based method is proposed for bulk-motion correction in variance imaging. Experiments were performed to demonstrate the effectiveness of the proposed method for 3-D vasculature imaging of human retina and choroid.

Paper Details

Date Published: 1 January 2010
PDF: 4 pages
J. Biomed. Opt. 15(1) 016029 doi: 10.1117/1.3302806
Published in: Journal of Biomedical Optics Volume 15, Issue 1
Show Author Affiliations
Lingfeng Yu, Carl Zeiss Meditec Inc. (United States)
Zhongping Chen, Beckman Laser Institute and Medical Clinic (United States)


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