Share Email Print

Journal of Biomedical Optics

Epidermal laser stimulation of action potentials in the frog sciatic nerve
Author(s): Nichole M. Jindra; Douglas Goddard; Michelle L. Imholte; Robert J. Thomas
Format Member Price Non-Member Price
PDF $20.00 $25.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Measurements of laser-stimulated action potentials in the sciatic nerve of leopard frogs (Rana pipiens) are made using two infrared lasers. The dorsal sides of the frog's hind limbs are exposed to short-pulsed 1540- and 1064-nm wavelengths at three separate spot sizes: 2, 3, and 4 mm. Energy density thresholds are determined for eliciting an action potential at each experimental condition. Results from these exposures show similar evoked potential thresholds for both wavelengths. The 2-mm-diam spot sizes yield action potentials at radiant exposure levels almost double that seen with larger beam sizes.

Paper Details

Date Published: 1 January 2010
PDF: 6 pages
J. Biomed. Opt. 15(1) 015002 doi: 10.1117/1.3292014
Published in: Journal of Biomedical Optics Volume 15, Issue 1
Show Author Affiliations
Nichole M. Jindra, Air Force Research Lab. (United States)
Douglas Goddard, Northrop Grumman Mission Systems (United States)
Michelle L. Imholte, Northrop Grumman Mission Systems (United States)
Robert J. Thomas, Air Force Research Lab. (United States)

© SPIE. Terms of Use
Back to Top