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Journal of Biomedical Optics • Open Access

Doppler optical coherence tomography for interventional cardiovascular guidance: in vivo feasibility and forward-viewing probe flow phantom demonstration
Author(s): Nigel R. Munce; Graham A. Wright; Adrian Mariampillai; Beau A. Standish; Michael K. K. Leung; Louis Tan; Kenneth K.C. Lee; Brian K. Courtney; Aaron A. Teitelbaum; Bradley H. Strauss; I. Alex Vitkin; Victor Xiao Dong Yang

Paper Abstract

We demonstrate the potential of a forward-looking Doppler optical coherence tomography (OCT) probe for color flow imaging in several commonly seen narrowed artery morphologies. As a proof of concept, we present imaging results of a surgically exposed thrombotic occlusion model that was imaged superficially to demonstrate that Doppler OCT can identify flow within the recanalization channels of a blocked artery. We present Doppler OCT images in which the flow is nearly antiparallel to the imaging direction. These images are acquired using a flexible 2.2-mm-diam catheter that used electrostatic actuation to scan up to 30 deg ahead of the distal end. Doppler OCT images of physiologically relevant flow phantoms consisting of small channels and tapered entrance geometries are demonstrated.

Paper Details

Date Published: 1 January 2010
PDF: 7 pages
J. Biomed. Opt. 15(1) 011103 doi: 10.1117/1.3292007
Published in: Journal of Biomedical Optics Volume 15, Issue 1
Show Author Affiliations
Nigel R. Munce, Univ. of Toronto (Canada)
Graham A. Wright, Sunnybrook Health Sciences Ctr. (Canada)
Adrian Mariampillai, Univ. of Toronto (Canada)
Beau A. Standish, Ryerson Univ. (Canada)
Michael K. K. Leung, Univ. of Toronto (Canada)
Louis Tan, Univ. of Toronto (Canada)
Kenneth K.C. Lee, Univ. of Toronto (Canada)
Brian K. Courtney, Sunnybrook Health Sciences Ctr. (Canada)
Aaron A. Teitelbaum, Sunnybrook Health Sciences Ctr. (Canada)
Bradley H. Strauss, Sunnybrook Health Sciences Ctr. (Canada)
I. Alex Vitkin, Univ. of Toronto (Canada)
Victor Xiao Dong Yang, Ryerson Univ. (Canada)

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