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Journal of Biomedical Optics

Spectral filtering in pulsed photothermal temperature profiling of collagen tissue phantoms
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Paper Abstract

We present an experimental comparison of pulsed photothermal (PPT) profiling in collagen-based tissue phantoms utilizing different midinfrared spectral bands. Laser-induced temperature profiles are reconstructed using a custom optimization code within the customary monochromatic approximation. Both experimental results and a detailed numerical simulation of the procedure demonstrate that, despite the associated reduction of signal-to-noise ratio, appropriate spectral filtering reduces the broadening of temperature peaks and thus improves the accuracy of temperature profiling. For our experimental system, best performance is obtained when applying a long-pass filter with cut-on wavelength at 3.4-3.8 μm. Because our collagen gel mimics infrared and thermal properties of human skin, we believe that this conclusion is transferrable to PPT radiometric profiling of human skin in vivo.

Paper Details

Date Published: 1 November 2009
PDF: 8 pages
J. Biomed. Opt. 14(6) 064024 doi: 10.1117/1.3275465
Published in: Journal of Biomedical Optics Volume 14, Issue 6
Show Author Affiliations
Matija Milanic, Jožef Stefan Institute (Slovenia)
Boris Majaron, Jožef Stefan Institute (Slovenia)

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