Share Email Print
cover

Journal of Biomedical Optics

Reflection-contrast limit of fiber-optic image guides
Author(s): Pierre M. Lane; Calum E. MacAulay
Format Member Price Non-Member Price
PDF $20.00 $25.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Fiber-optic image guides in confocal reflectance endomicroscopes introduce background backscatter that limits the achievable contrast in these devices. We show the dominant source of backscatter from the image guide is due to Rayleigh scattering at short wavelengths and terminal reflections of the fibers at long wavelengths. The effective Rayleigh scattering coefficient and the wavelength-independent reflectivity due terminal reflections are measured experimentally in a commercial image guide. The Rayleigh scattering component of backscatter can be accurately predicted using the fractional refractive-index difference and length of the fibers in the image guide. We also presented a simple model that can be used to predict signal-to-background ratio in a fiber-optic confocal reflectance endomicroscope for biologically relevant tissues and contrast agents that cover a wide range of reflectivity.

Paper Details

Date Published: 1 November 2009
PDF: 7 pages
J. Biomed. Opt. 14(6) 064028 doi: 10.1117/1.3269679
Published in: Journal of Biomedical Optics Volume 14, Issue 6
Show Author Affiliations
Pierre M. Lane, The BC Cancer Research Ctr. (Canada)
Calum E. MacAulay, The BC Cancer Research Ctr. (Canada)


© SPIE. Terms of Use
Back to Top