Share Email Print
cover

Journal of Biomedical Optics

Dynamic eye phantom for retinal oximetry measurements
Format Member Price Non-Member Price
PDF $20.00 $25.00

Paper Abstract

Measurements of oxygen saturation and flow in the retina can yield information about eye health and the onset of eye pathologies such as diabetic retinopathy. Recently, we developed a multiaperture camera that uses the division of the retinal image into several wavelength-sensitive subimages to compute retinal oxygen saturation. The calibration of such instruments is particularly difficult due to the layered structure of the eye and the lack of alternative measurement techniques. For this purpose, we realize an in vitro model of the human eye composed of a lens, the retina vessel, and three layers: the choroid, the retinal pigmented epithelium, and the sclera. The retinal vessel is modeled with a microtube connected to a micropump and a hemoglobin reservoir in a closed circulatory system. Hemoglobin oxygenation in the vessel could be altered using a reversible fuel cell. The sclera is represented by a Spectralon slab. The optical properties of the other layers are mimicked using titanium dioxide as a scatterer, ink as an absorber, and epoxy as a supporting structure. The optical thickness of each layer of the eye phantom is matched to each respective eye layer.

Paper Details

Date Published: 1 November 2009
PDF: 6 pages
J. Biomed. Opt. 14(6) 064008 doi: 10.1117/1.3258669
Published in: Journal of Biomedical Optics Volume 14, Issue 6
Show Author Affiliations
Paul Lemaillet, The Catholic Univ. of America (United States)
Jessica C. Ramella-Roman, The Catholic Univ. of America (United States)


© SPIE. Terms of Use
Back to Top