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Journal of Biomedical Optics

Comparison of diffusion approximation and higher order diffusion equations for optical tomography of osteoarthritis
Author(s): Zhen Yuan; Qizhi Zhang; Eric S. Sobel; Huabei Jiang
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Paper Abstract

In this study, a simplified spherical harmonics approximated higher order diffusion model is employed for 3-D diffuse optical tomography of osteoarthritis in the finger joints. We find that the use of a higher-order diffusion model in a stand-alone framework provides significant improvement in reconstruction accuracy over the diffusion approximation model. However, we also find that this is not the case in the image-guided setting when spatial prior knowledge from x-rays is incorporated. The results show that the reconstruction error between these two models is about 15 and 4%, respectively, for stand-alone and image-guided frameworks.

Paper Details

Date Published: 1 September 2009
PDF: 8 pages
J. Biomed. Opt. 14(5) 054013 doi: 10.1117/1.3233655
Published in: Journal of Biomedical Optics Volume 14, Issue 5
Show Author Affiliations
Zhen Yuan, Univ. of Florida (United States)
Qizhi Zhang, Univ. of Florida (United States)
Eric S. Sobel, Univ. of Florida (United States)
Huabei Jiang, Univ. of Florida (United States)

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