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Journal of Biomedical Optics • Open Access

Photoacoustic technique for assessing optical scattering properties of turbid media
Author(s): Janaka C. Ranasinghesagara; Yan Jian; Xuhui Chen; Kory Mathewson; Roger J. Zemp

Paper Abstract

Measurement of tissue optical properties impacts both optical diagnostic and theraputic applications. Although existing photoacoustic imaging techniques provide optical absorption contrast, we present a photoacoustic technique that demonstrates sensitivity to the optical scattering coefficient of a turbid medium. By incrementing the distance between a surface illumination spot and a subsurface absorber and measuring the photoacoustic amplitude of the absorber, we can effectively estimate the Green's function of light transport in a turbid medium. Our results for different concentrations of Intralipid indicate that this technique has the ability to distinguish small changes of the reduced scattering coefficient. It has the potential to be used for in vivo studies to obtain reduced scattering coefficients of biological tissues. These findings will potentially improve the calculation of subcutaneous fluence in photoacoustic-based techniques and laser dosimetry studies in live tissues.

Paper Details

Date Published: 1 July 2009
PDF: 3 pages
J. Biomed. Opt. 14(4) 040504 doi: 10.1117/1.3200922
Published in: Journal of Biomedical Optics Volume 14, Issue 4
Show Author Affiliations
Janaka C. Ranasinghesagara, Univ. of Alberta (Canada)
Yan Jian, Univ. of Alberta (Canada)
Xuhui Chen, Univ. of Alberta (Canada)
Kory Mathewson, Univ. of Alberta (Canada)
Roger J. Zemp, Univ. of Alberta (Canada)

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