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Journal of Biomedical Optics • Open Access

In vivo trans-rectal ultrasound-coupled optical tomography of a transmissible venereal tumor model in the canine pelvic canal
Author(s): Zhen Jiang; G. Reed Holyoak; Kenneth Eugene Bartels; Jerry W. Ritchey; Guan Xu; Charles F. Bunting; Gennady Slobodov; Daqing Piao

Paper Abstract

In vivo trans-rectal near-infrared (NIR) optical tomography was performed concurrently with, albeit reconstructed without spatial a prior of, trans-rectal ultrasound (US) on transmissible venereal tumor (TVT) developed as a model in the canine pelvic canal. Studies were taken longitudinally at prior to, 14 days after, and 35 days after the TVT injection. As the tumor grew, the nodules became increasingly hyperabsorptive and moderately hyperscattering on NIR. The regions of strong NIR contrast, especially on absorption images, correlated well with those of US hypoechoic masses indicative of tumors. Combining the information of trans-rectal NIR and US detected the tumor more accurately than did the US alone at 14 days postinjection.

Paper Details

Date Published: 1 May 2009
PDF: 3 pages
J. Biomed. Opt. 14(3) 030506 doi: 10.1117/1.3149852
Published in: Journal of Biomedical Optics Volume 14, Issue 3
Show Author Affiliations
Zhen Jiang, Oklahoma State Univ. (United States)
G. Reed Holyoak, Oklahoma State Univ. (United States)
Kenneth Eugene Bartels, Oklahoma State Univ. (United States)
Jerry W. Ritchey, Oklahoma State Univ. (United States)
Guan Xu, Oklahoma State Univ. (United States)
Charles F. Bunting, Oklahoma State Univ. (United States)
Gennady Slobodov, Univ. of Oklahoma Health Sciences Ctr. (United States)
Daqing Piao, Oklahoma State Univ. (United States)

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