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Journal of Biomedical Optics

Photoacoustic tomography of the mouse cerebral cortex with a high-numerical-aperture-based virtual point detector
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Paper Abstract

The mouse cerebral cortex was imaged in situ by photoacoustic tomography (PAT). Instead of a flat ultrasonic transducer, a virtual point detector based on a high numerical aperture (NA), positively focused transducer was used. This virtual point detector has a wide omnidirectional acceptance angle, a high sensitivity, and a negligible aperture effect. In addition, the virtual point detector can be located much more closely to the object during the detection. Compared with a finite-size flat transducer, images generated by using this virtual point detector have both uniform signal-to-noise ratio (SNR) and resolution.

Paper Details

Date Published: 1 March 2009
PDF: 3 pages
J. Biomed. Opt. 14(2) 024047 doi: 10.1117/1.3122365
Published in: Journal of Biomedical Optics Volume 14, Issue 2
Show Author Affiliations
Changhui Li, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)

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