Share Email Print
cover

Journal of Biomedical Optics

Rapid identification of anterior and posterior root of cauda equina nerves by near-infrared diffuse reflectance spectroscopy
Author(s): Shaofei Xie; BingRen Xiang; ShouShan Bu; Xiaojian Cao; Ye Ye; Jun Lu; Haishan Deng
Format Member Price Non-Member Price
PDF $20.00 $25.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

A new rapid chemometric method has been developed to identify the anterior and posterior roots of cauda equina nerves by near-infrared (NIR) diffuse reflectance spectroscopy. NIR spectra of nerves were measured using a Fourier transform NIR spectrometer equipped with a fiber-optic probe. The result revealed no observable difference in the spectra between the anterior and posterior root samples, but the two roots could be identified by cluster analysis based on the differences of their spectral features. The overall accuracy of the cluster analysis model was 87.5%, and the accuracy for the actual anterior root and actual posterior root were 95% and 80%, respectively. The result suggested that NIR spectroscopy in combination with the chemometrics method (cluster analysis) could be used to classify the anterior and posterior roots of cauda equina nerves. The proposed method required only a few minutes, while classical methods commonly required at least one hour. It was demonstrated that the new method could provide a rapid, correct, nondestructive and low-cost potential means to quickly differentiate anterior and posterior roots in mixed cauda equina nerves, which would be helpful for surgeons to align nerve stumps correctly.

Paper Details

Date Published: 1 March 2009
PDF: 7 pages
J. Biomed. Opt. 14(2) 024005 doi: 10.1117/1.3086611
Published in: Journal of Biomedical Optics Volume 14, Issue 2
Show Author Affiliations
Shaofei Xie, China Pharmaceutical Univ. (China)
BingRen Xiang, China Pharmaceutical Univ. (China)
ShouShan Bu, Nanjing Medical Univ. (China)
Xiaojian Cao, Nanjing Medical Univ. (China)
Ye Ye, China Pharmaceutical Univ. (China)
Jun Lu, China Pharmaceutical Univ. (China)
Haishan Deng, Nanjing Univ. of Traditional Chinese Medicine (China)


© SPIE. Terms of Use
Back to Top