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Journal of Biomedical Optics

Compact portable ocular microtremor sensor: design, development and calibration
Author(s): James Patrick Ryle; Mohammed Ali Al-Kalbani; Niamh Collins; Unnikrishnan Gopinathan; Gerard Boyle; Davis Coakley; John T. Sheridan
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Paper Abstract

Ocular microtremor (OMT) is a physiological high-frequency (up to 150 Hz) low-amplitude (25–2500 nm peak-to-peak) involuntary motion of the human eye. Recent studies suggest a number of clinical applications for OMT that include monitoring the depth of anesthesia of a patient in surgery, prediction of outcome in coma, and diagnosis of brain stem death. Clinical OMT investigations to date have used mechanical piezoelectric probes or piezoelectric strain gauges that have many drawbacks which arise from the fact that the probe is in contact with the eye. We describe the design of a compact noncontact sensing device to measure OMT that addresses some of the above drawbacks. We evaluate the system performance using a calibrated piezoelectric vibrator that simulates OMT signals under conditions that can occur in practice, i.e., wet eye conditions. We also test the device at low light levels well within the eye safety range.

Paper Details

Date Published: 1 January 2009
PDF: 12 pages
J. Biomed. Opt. 14(1) 014021 doi: 10.1117/1.3083435
Published in: Journal of Biomedical Optics Volume 14, Issue 1
Show Author Affiliations
James Patrick Ryle, Univ. College Dublin (Ireland)
Mohammed Ali Al-Kalbani, Trinity College Dublin (Ireland)
Niamh Collins, Trinity College Dublin (Ireland)
Unnikrishnan Gopinathan, Univ. Stuttgart (Germany)
Gerard Boyle, Trinity College Dublin (Ireland)
Davis Coakley, Trinity College Dublin (Ireland)
John T. Sheridan, Univ. College Dublin (Ireland)

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