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Journal of Biomedical Optics

Analysis of the fluorescence temporal point-spread function in a turbid medium and its application to optical imaging
Author(s): Sung-Ho Han; Salman Farshchi-Heydari; David J. Hall
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Paper Abstract

A time-domain optical method to evaluate the concentration (n), lifetime (τ), and depth (d) of a fluorescent inclusion is described by the complete analysis of the fluorescence temporal point-spread function (TPSF). The behavior of parameters in the fluorescence TPSF is explored, and we demonstrate the method with experimental data from a localized fluorescent inclusion in scattering media to recover images of n, τ, and d. The method has potential application for in vivo fluorescence imaging.

Paper Details

Date Published: 1 November 2008
PDF: 6 pages
J. Biomed. Opt. 13(6) 064038 doi: 10.1117/1.3042271
Published in: Journal of Biomedical Optics Volume 13, Issue 6
Show Author Affiliations
Sung-Ho Han, Univ. of California, San Diego (United States)
Salman Farshchi-Heydari, Univ. of California, San Diego (United States)
David J. Hall, Univ. of California, San Diego (United States)


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