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Journal of Biomedical Optics

Image reconstruction method for a two-layer tissue structure accounts for chest-wall effects in breast imaging
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Paper Abstract

We develop a new tomographic imaging reconstruction algorithm for a two-layer tissue structure. Simulations and phantom experiments show more accurate reconstruction of target optical properties compared with those results obtained from a semi-infinite tissue model for layered structures. This improvement is mainly attributed to the more accurate estimation of background optical properties and more accurate estimation of weight matrix for imaging reconstruction by considering the light propagation effect in the second layer. Clinical results of breast lesions are also presented to demonstrate the utility of this new imaging algorithm.

Paper Details

Date Published: 1 November 2008
PDF: 13 pages
J. Biomed. Opt. 13(6) 064029 doi: 10.1117/1.3041497
Published in: Journal of Biomedical Optics Volume 13, Issue 6
Show Author Affiliations
Chen Xu, Univ. of Connecticut (United States)
Mini Das, Univ. of Massachusetts Medical School (United States)
Yasaman Ardeshirpour, Univ. of Connecticut (United States)
Quing Zhu, Univ. of Connecticut (United States)

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