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Journal of Biomedical Optics

Quantification of scattering changes using polarization-sensitive optical coherence tomography
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Paper Abstract

We demonstrate that changes in the degree of polarization (DOP) depend on changes in the scattering coefficient, and they can be quantified by using a polarization-sensitive optical coherence tomography (PS-OCT) system. We test our hypothesis using liquid and solid phantoms made from Intralipid suspensions and gelatin, respectively. We also quantify the DOP changes with depth caused by changes in the concentration of scatterers in the liquid and solid phantoms. It is clearly shown that the DOP change has a linear relationship with the scattering change. In our previous study, we showed that the axial slope of the DOP is different between normal and pathologic cervical tissues. Our results demonstrate that the quantification of the axial DOP slope can be used for the systematic diagnosis of certain tissue pathology.

Paper Details

Date Published: 1 September 2008
PDF: 6 pages
J. Biomed. Opt. 13(5) 054032 doi: 10.1117/1.2976430
Published in: Journal of Biomedical Optics Volume 13, Issue 5
Show Author Affiliations
Sang-Won Lee, Yonsei Univ. (Korea, Republic of)
Jin-Ho Kang, Yonsei Univ. (Korea, Republic of)
Ji-Yeong Yoo, Yonsei Univ. (Korea, Republic of)
Moon-Sik Kang, Yonsei Univ. (Korea, Republic of)
Jung-Taek Oh, Samsung Electronics Co., Ltd. (Korea, Republic of)
Beop-Min Kim, Yonsei Univ. (Korea, Republic of)


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