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Journal of Biomedical Optics • Open Access

Imaging pulsatile retinal blood flow in human eye
Author(s): Bin Rao; Lingfeng Yu; Huihua Kenny Chiang; Leandro C. Zacharias; Ronald Michael Kurtz; Baruch D. Kuppermann; Zhongping Chen

Paper Abstract

A functional Fourier domain optical coherence tomography instrument offering spectral Doppler imaging of in vivo pulsatile human retinal blood flow was constructed. An improved phase-resolved algorithm was developed to correct bulk motion artifacts. Spectral Doppler imaging provides complementary temporal flow information to the spatially distributed flow information of the color Doppler image by providing direct visualization of the Doppler spectrum of the flow whose pattern can be further quantified with various velocity envelope curves and their corresponding flow indices. The coefficient of repeatability on resistance index measurement was assessed by analyzing 14 measurements on two vessels within two normal subjects.

Paper Details

Date Published: 1 July 2008
PDF: 3 pages
J. Biomed. Opt. 13(4) 040505 doi: 10.1117/1.2967986
Published in: Journal of Biomedical Optics Volume 13, Issue 4
Show Author Affiliations
Bin Rao, Univ. of California, Irvine (United States)
Lingfeng Yu, Univ. of California, Irvine (United States)
Huihua Kenny Chiang, National Yang-Ming Univ. (Taiwan)
Leandro C. Zacharias, Univ. of California, Irvine (United States)
Ronald Michael Kurtz, Univ. of California/Irvine (United States)
Baruch D. Kuppermann, Univ. of California, Irvine (United States)
Zhongping Chen, Univ. of California, Irvine (United States)

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