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Journal of Biomedical Optics • Open Access

Handheld forward-imaging needle endoscope for ophthalmic optical coherence tomography inspection
Author(s): Shuo Han; Marinko V. Sarunic; Jigang Wu; Mark S. Humayun; Changhuei Yang

Paper Abstract

We report the narrowest to-date (21 gauge, 820-μm-diam) handheld forward-imaging optical coherence tomography (OCT) needle endoscope and demonstrate its feasibility for ophthalmic OCT inspection. The probe design is based on paired-angle-rotation scanning (PARS), which enables a linear B-scan pattern in front of the probe tip by using two counterrotating angle polished gradient-index (GRIN) lenses. Despite its small size, the probe can provide a numerical apertune (NA) of 0.22 and an experimental sensitivity of 92 dB at 0.5 frame/s. The feasibility of retinal imaging is tested on enucleated ex vivo porcine eyes, where structural features including remnant vitreous humor, retina, and choroid can be clearly distinguished. Due to its imaging quality comparable to a commercial OCT system and compatibility with the current ophthalmic surgery standard, the probe can potentially serve as a better alternative to traditional visual inspection by white light illumination during vitreoretinal surgery (e.g., vitrectomy).

Paper Details

Date Published: 1 March 2008
PDF: 3 pages
J. Biomed. Opt. 13(2) 020505 doi: 10.1117/1.2904664
Published in: Journal of Biomedical Optics Volume 13, Issue 2
Show Author Affiliations
Shuo Han, California Institute of Technology (United States)
Marinko V. Sarunic, Simon Fraser Univ. (Canada)
Jigang Wu, California Institute of Technology (United States)
Mark S. Humayun, Univ. of Southern California (United States)
Changhuei Yang, California Institute of Technology (United States)

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