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Journal of Biomedical Optics • Open Access

In vivo confocal and multiphoton microendoscopy
Author(s): Pilhan Kim; Mehron Pouris'haag; Daniel Cote; Charles P. Lin; Seok-Hyun Yun

Paper Abstract

The ability to conduct high-resolution fluorescence imaging in internal organs of small animal models in situ and over time can make a significant impact in biomedical research. Toward this goal, we developed a real-time confocal and multiphoton endoscopic imaging system. Using 1-mm-diameter endoscopes based on gradient index lenses, we demonstrate video-rate multicolor multimodal imaging with cellular resolution in live mice.

Paper Details

Date Published: 1 January 2008
PDF: 3 pages
J. Biomed. Opt. 13(1) 010501 doi: 10.1117/1.2839043
Published in: Journal of Biomedical Optics Volume 13, Issue 1
Show Author Affiliations
Pilhan Kim, Massachusetts General Hospital (United States)
Mehron Pouris'haag, Massachusetts General Hospital (United States)
Daniel Cote, Massachusetts General Hospital (United States)
Charles P. Lin, Massachusetts General Hospital (United States)
Seok-Hyun Yun, Massachusetts General Hospital (United States)


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