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Journal of Biomedical Optics

Matrix-assisted pulsed laser evaporation of poly(D,L-lactide) for biomedical applications: effect of near infrared radiation
Author(s): Valeria Califano; Francesco Bloisi; Luciano Rosario Maria Vicari; Oana Bretcanu; Aldo R. Boccaccini
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Paper Abstract

The deposition of thin films of poly(D,L-lactide) (PDLLA) by using the matrix-assisted pulsed laser evaporation (MAPLE) technique is investigated. PDLLA is a highly biocompatible and biodegradable polymer, with wide applicability in the biomedical field. The laser wavelength used in the MAPLE process is optimized to obtain a good-quality deposition. The structure of the polymer film is analyzed by Fourier transform infrared spectroscopy (FTIR). It is found that the chemical structure of PDLLA undergoes little or no damage during deposition with near-infrared laser radiation (1064 nm). It is thus confirmed that at this wavelength, the MAPLE technique can be applied for fragile biopolymer molecules, which are easily damaged by other laser radiations (UV radiation). This method allows future development of tailored polymer coatings for biomedical applications.

Paper Details

Date Published: 1 January 2008
PDF: 6 pages
J. Biomed. Opt. 13(1) 014028 doi: 10.1117/1.2830660
Published in: Journal of Biomedical Optics Volume 13, Issue 1
Show Author Affiliations
Valeria Califano, Univ. degli Studi di Napoli Federico II (Italy)
Francesco Bloisi, Univ. di Napoli Federico II (Italy)
Luciano Rosario Maria Vicari, Univ. di Napoli Federico II (Italy)
Oana Bretcanu, Imperial College London (United Kingdom)
Aldo R. Boccaccini, Imperial College London (United Kingdom)

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