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Journal of Biomedical Optics • Open Access

Path-length-resolved optical Doppler perfusion monitoring

Paper Abstract

We report the first path-length-resolved perfusion measurements on human skin measured with a phase-modulated low-coherence Mach-Zehnder interferometer with spatially separated fibers for illumination and detection. Optical path lengths of Doppler shifted and unshifted light and path-length-dependent Doppler broadening of multiply scattered light from skin are measured from the Doppler broadened interference peaks appearing in the power spectrum. Perfusion and its variations during occlusion are measured in real time for a given optical path length, and the results are compared with the perfusion signal obtained with a conventional laser Doppler perfusion monitor.

Paper Details

Date Published: 1 November 2007
PDF: 3 pages
J. Biomed. Opt. 12(6) 060508 doi: 10.1117/1.2823141
Published in: Journal of Biomedical Optics Volume 12, Issue 6
Show Author Affiliations
Babu Varghese, Univ. Twente (Netherlands)
Vinayakrishnan Rajan, Univ. Twente (Netherlands)
Ton G. van Leeuwen, Univ. Twente (Netherlands)
Wiendelt Steenbergen, Univ. Twente (Netherlands)

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