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Journal of Biomedical Optics • Open Access

Three-dimensional optical coherence tomography at 1050 nm versus 800 nm in retinal pathologies: enhanced performance and choroidal penetration in cataract patients
Author(s): Boris Povazay; Boris M. Hermann; Angelika Unterhuber; Bernd Hofer; Harald Sattmann; Florian Zeiler; James E. Morgan; Christiane Falkner-Radler; Carl Glittenberg; Susanne Binder; Wolfgang Drexler

Paper Abstract

Frequency domain optical coherence tomography (FD-OCT), based on an all-reflective high-speed InGaAs spectrometer, operating in the 1050 nm wavelength region for retinal diagnostics, enables high-speed, volumetric imaging of retinal pathologies with greater penetration into choroidal tissue is compared to conventional 800 nm three-dimensional (3-D) ophthalmic FD-OCT systems. Furthermore, the lower scattering at this wavelength significantly improves imaging performance in cataract patients, thereby widening the clinical applicability of ophthalmic OCT. The clinical performance of two spectrometer-based ophthalmic 3-D OCT systems compared in respect to their clinical performance, one operating at 800 nm with 150 nm bandwidth (~3 µm effective axial resolution) and the other at 1050 nm with 70 nm bandwidth (~7 µm effective axial resolution). Results achieved with 3-D OCT at 1050 nm reveal, for the first time, decisive improvements in image quality for patients with retinal pathologies and clinically significant cataract.

Paper Details

Date Published: 1 July 2007
PDF: 7 pages
J. Biomed. Opt. 12(4) 041211 doi: 10.1117/1.2773728
Published in: Journal of Biomedical Optics Volume 12, Issue 4
Show Author Affiliations
Boris Povazay, Cardiff Univ. (United Kingdom)
Boris M. Hermann, Cardiff Univ. (United Kingdom)
Angelika Unterhuber, Cardiff Univ. (United Kingdom)
Bernd Hofer
Harald Sattmann, Medizinische Univ. Wien (Austria)
Florian Zeiler, Ludwig Boltzmann Institut (Austria)
James E. Morgan, Cardiff Univ. (United Kingdom)
Christiane Falkner-Radler, Ludwig Boltzmann Institut (Austria)
Carl Glittenberg, Ludwig Boltzmann Institut (Austria)
Susanne Binder, Ludwig Boltzmann Institut (Austria)
Wolfgang Drexler, Cardiff Univ. (United Kingdom)

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