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Journal of Biomedical Optics

Novel flexible light diffuser and irradiation properties for photodynamic therapy
Author(s): Bärbel Selm; Markus Rothmaier; Martin Camenzind; Tania N. Khan; Heinrich Walt
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Paper Abstract

Many current light diffusers for photodynamic therapy are inflexible, and the applied light dose is difficult to adjust during treatment, especially on complex body surfaces. A thin and flexible luminous textile is developed using plastic optical fibers as a light distributor. The textile diffuser is evaluated for flexibility, irradiance, brightness distribution, and temperature rise with a 652-nm laser set to 100 mW. The bending force of the textile diffuser resembles a defined optical film. On the textile surface, an average output power of 3.6±0.6 mW/cm2 is measured, corresponding to a transmission rate of 40±3.8% on an area of 11 cm2. Aluminum backing enhances the irradiance to the face (treatment side). The measured brightness distribution seems to lie within a range similar to other photodynamic therapy (PDT) devices. A power setting of 100 mW increases the temperature of the textile diffuser surface of up to 27°C, and 1 W raises the temperature above 40°C. Results confirm that the flexible textile diffuser supplies suitable radiation for low fluence rate photodynamic therapy on an area of several cm2.

Paper Details

Date Published: 1 May 2007
PDF: 7 pages
J. Biomed. Opt. 12(3) 034024 doi: 10.1117/1.2749737
Published in: Journal of Biomedical Optics Volume 12, Issue 3
Show Author Affiliations
Bärbel Selm, EMPA (Switzerland)
Markus Rothmaier, EMPA (Switzerland)
Martin Camenzind, EMPA (Switzerland)
Tania N. Khan, Univ. Hospital Zürich (Switzerland)
Heinrich Walt, Univ. Hospital Zürich (Switzerland)

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