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Journal of Biomedical Optics

Measurement of visco-elastic properties of breast-tissue mimicking materials using diffusing wave spectroscopy
Author(s): C. Usha Devi; R. S. Bharat Chandran; Ram M. Vasu; Ajay K. Sood
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Paper Abstract

Diffusing wave spectroscopy (DWS), without the use of tracer particles, has been used to study the internal dynamics of polyvinyl alcohol (PVA) phantoms, which mimic the properties of normal and malignant breast tissues. From the measured intensity autocorrelations, the mean square displacement (MSD) of phantom meshing is estimated, leading to the storage and loss moduli of the medium covering frequencies up to 10 KHz. These are verified with independent measurements from a dynamic mechanical analyzer (DMA) at low frequencies. We thus prove the usefulness of DWS to extract visco-elastic properties of the phantom and its possible application in detecting malignancy in soft tissues.

Paper Details

Date Published: 1 May 2007
PDF: 5 pages
J. Biomed. Opt. 12(3) 034035 doi: 10.1117/1.2743081
Published in: Journal of Biomedical Optics Volume 12, Issue 3
Show Author Affiliations
C. Usha Devi, Indian Institute of Science (India)
R. S. Bharat Chandran, Indian Institute of Science (India)
Ram M. Vasu, Indian Institute of Science (India)
Ajay K. Sood, Indian Institute of Science (India)

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