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Journal of Biomedical Optics

Absorption of collagen: effects on the estimate of breast composition and related diagnostic implications
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Paper Abstract

The absorption spectrum of collagen powder is measured between 610 and 1040 nm by time-resolved transmittance spectroscopy. Absorption spectra of breast from healthy volunteers are then interpreted, adding collagen to the other absorbers previously considered (i.e., oxy- and deoxyhemoglobin, water, and lipids). A significant amount of collagen, depending on breast type, is estimated to be present. Adding collagen to the fitting procedure affects remarkably the estimated values of blood content and oxygenation. The quantification of collagen has potential implications for the assessment of breast density and cancer risk.

Paper Details

Date Published: 1 January 2007
PDF: 4 pages
J. Biomed. Opt. 12(1) 014021 doi: 10.1117/1.2699170
Published in: Journal of Biomedical Optics Volume 12, Issue 1
Show Author Affiliations
Paola Taroni, Politecnico di Milano (Italy)
Daniela Comelli, Politecnico di Milano (Italy)
Antonio Pifferi, Politecnico di Milano (Italy)
Alessandro Torricelli, Politecnico di Milano (Italy)
Rinaldo Cubeddu, Politecnico di Milano (Italy)

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