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Journal of Biomedical Optics

Improving performance of reflectance diffuse optical imaging using a multicentered mode
Author(s): Qing Zhao; Lijun Ji; Tianzi Jiang
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Paper Abstract

We propose a novel multicentered mode for arrangement of optical fibers to improve the imaging performance of reflectance diffuse optical imaging (rDOI). Simulations performed using a semi-infinite model show that the proposed multicentered geometries can achieve a maximum of 42 overlapping measurements. The contrast-to-noise ratio (CNR) analysis indicates that the best spatial resolution is 1 mm in radius and the contrast resolution is less than 1.05 for the multicentered geometries. The results from simulations indicate significant improvement in image quality compared to the single-centered mode and previous geometries. Additional experimental results on a single human subject lead to the conclusion that the proposed multicentered geometries are appropriate for exploring activations in the human brain. From the results of this research, we conclude that the proposed multicentered mode could advance the performance of rDOI both in image quality and practical convenience.

Paper Details

Date Published: 1 November 2006
PDF: 8 pages
J. Biomed. Opt. 11(6) 064019 doi: 10.1117/1.2400703
Published in: Journal of Biomedical Optics Volume 11, Issue 6
Show Author Affiliations
Qing Zhao, Institute of Automation (China)
Lijun Ji, Institute of Automation (China)
Tianzi Jiang, Institute of Automation (China)

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