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Journal of Biomedical Optics • Open Access

Myocardial tissue characterization based on a polarization-sensitive optical coherence tomography system with an ultrashort pulsed laser
Author(s): Chia-Wei Sun; Yih-Ming Wang; Long-Sheng Lu; Chih-Wei Lu; I-Jen Hsu; Meng-Tsan Tsai; Chih-Chung Yang; Yean-Woei Kiang; Chau-Chung Wu

Paper Abstract

A polarization-sensitive optical coherence tomography (PSOCT) system using a femtosecond-laser as the broadband light source is implemented with the axial resolution of 5 µm in free space. Through the design of path-length difference between the two polarization inputs and the modulation of one of the polarization inputs, the PSOCT images of various input and output polarization combinations can be distinguished and simultaneously collected. The PSOCT system is then used for in vitro scanning of the myocardium tissues of normal and infarcted rat hearts. The destruction of the birefringence nature of the fiber muscle in the infarcted heart can be clearly observed.

Paper Details

Date Published: 1 September 2006
PDF: 7 pages
J. Biomed. Opt. 11(5) 054016 doi: 10.1117/1.2363358
Published in: Journal of Biomedical Optics Volume 11, Issue 5
Show Author Affiliations
Chia-Wei Sun, National Taiwan Univ. (Taiwan)
Yih-Ming Wang, National Taiwan Univ. (Taiwan)
Long-Sheng Lu, National Taiwan Univ. (Taiwan)
Chih-Wei Lu, National Taiwan Univ. (Taiwan)
I-Jen Hsu, National Taiwan Univ. (Taiwan)
Meng-Tsan Tsai, National Taiwan Univ. (Taiwan)
Chih-Chung Yang, National Taiwan Univ. (Taiwan)
Yean-Woei Kiang, National Taiwan Univ. (Taiwan)
Chau-Chung Wu, National Taiwan Univ. (Taiwan)

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