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Journal of Biomedical Optics

Reliability of the compensation comparison method for measuring retinal stray light studied using Monte-Carlo simulations
Author(s): Joris Coppens; Luuk Franssen; Thomas J. T. P. van den Berg
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Paper Abstract

Recently the psychophysical compensation comparison method was developed for routine measurement of retinal stray light. The subject's responses to a series of two-alternative-forced-choice trials are analyzed using a maximum-likelihood (ML) approach assuming some fixed shape for the psychometric function (PF). This study evaluates the reliability of the method using Monte-Carlo simulations. Various sampling strategies were investigated, including the two-phase sampling strategy that is used in a commercially available instrument. Results are given for the effective dynamic range and measurement accuracy. The effect of a mismatch of the shape of the PF of an observer and the fixed shape used in the ML analysis was analyzed. Main outcomes are that the two-phase sampling scheme gives good precision (Standard deviation=0.07 logarithmic units on average) for estimation of the stray light value. Bias is virtually zero. Furthermore, a reliability index was derived from the responses and found to be effective.

Paper Details

Date Published: 1 September 2006
PDF: 12 pages
J. Biomed. Opt. 11(5) 054010 doi: 10.1117/1.2357731
Published in: Journal of Biomedical Optics Volume 11, Issue 5
Show Author Affiliations
Joris Coppens, The Netherlands Ophthalmic Research Institute (Netherlands)
Luuk Franssen, The Netherlands Ophthalmic Research Institute (Netherlands)
Thomas J. T. P. van den Berg, The Netherlands Ophthalmic Research Institute (Netherlands)

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