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Optical Engineering

Cancer diagnosis by microscopic axial super-resolving reconstruction approach of cytological and histological images
Author(s): Zeev Zalevsky; Eran Rossmann; Edmond Sabo; Ehud Rivlin; David Mendlovic
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Paper Abstract

We present an optical data reconstruction method to be used for cancer diagnostics via cytological and histological images. The approach allows realizing extended depth of focus and data compression using wavelet transformation that is realized optically with very low computational complexity. The extended depth of focus and the compressed images are generated out of a set of optically defocused images realized due to axial translation of the diagnosed sample. The extended depth of focus image may be used for 3-D cytological information display without stereo projection. Note that the extended depth of focus actually means super-resolving imaging, since getting out of focus means filtering the high band spatial frequencies within the image.

Paper Details

Date Published: 1 August 2006
PDF: 11 pages
Opt. Eng. 45(8) 083201 doi: 10.1117/1.2336413
Published in: Optical Engineering Volume 45, Issue 8
Show Author Affiliations
Zeev Zalevsky, Bar-Ilan Univ. (Israel)
Eran Rossmann, Tel-Aviv Univ. (Israel)
Edmond Sabo, Carmel Medical Ctr. (Israel)
Ehud Rivlin, Technion-Israel Institute of Technology (Israel)
David Mendlovic, Civcom Inc. (Israel)

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