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Journal of Biomedical Optics • Open Access

Monitoring sarcomere structure changes in whole muscle using diffuse light reflectance
Author(s): JinJun Xia; Amanda Weaver; David E. Gerrard; Gang Yao

Paper Abstract

Normal biomechanical and physiological functions of striated muscles are facilitated by the repeating sarcomere units. Light scattering technique has been used in studying single extracted muscle fibers. However, few studies, if any, have been conducted to investigate the possibility of using optical detection to examine sarcomere structure changes in whole muscles. We conducted a series of experiments to demonstrate that optical scattering properties measured in whole muscle are related to changes in sarcomere structure. These results suggest that photon migration technique has a potential for characterizing in vivo tissue ultrastructure changes in whole muscle.

Paper Details

Date Published: 1 July 2006
PDF: 3 pages
J. Biomed. Opt. 11(4) 040504 doi: 10.1117/1.2234278
Published in: Journal of Biomedical Optics Volume 11, Issue 4
Show Author Affiliations
JinJun Xia, Univ. of Missouri/Columbia (United States)
Amanda Weaver, Purdue Univ. (United States)
David E. Gerrard, Purdue Univ. (United States)
Gang Yao, Univ. of Missouri/Columbia (United States)

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