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Journal of Biomedical Optics • Open Access

Office-based optical coherence tomographic imaging of human vocal cords
Author(s): Shuguang Guo; River L. Hutchison; Ryan Patrick Jackson; Anu Kohli; Tristan Sharp; Elizabeth Orwin; Richard Campbell Haskell; Zhongping Chen; Brian Jet-Fei Wong

Paper Abstract

Optical coherence tomography (OCT) is an evolving noninvasive imaging modality and has been used to image the larynx during surgical endoscopy. The design of an OCT sampling device capable of capturing images of the human larynx during a typical office based laryngoscopy examination is discussed. Both patient's and physician's movements were addressed. In vivo OCT imaging of the human larynx is demonstrated. Though the long focal length limits the lateral resolution of the image, the basement membrane can still be readily distinguished. Office-based OCT has the potential to guide surgical biopsies, direct therapy, and monitor disease. This is a promising imaging modality to study the larynx.

Paper Details

Date Published: 1 May 2006
PDF: 3 pages
J. Biomed. Opt. 11(3) 030501 doi: 10.1117/1.2200371
Published in: Journal of Biomedical Optics Volume 11, Issue 3
Show Author Affiliations
Shuguang Guo, Univ. of California/Irvine (United States)
River L. Hutchison, Beckman Laser Institute and Medical Clinic (United States)
Ryan Patrick Jackson, Univ. of California/Irvine (United States)
Anu Kohli, Univ. of California/Irvine (United States)
Tristan Sharp, Harvey Mudd College (United States)
Elizabeth Orwin, Harvey Mudd College (United States)
Richard Campbell Haskell, Harvey Mudd College (United States)
Zhongping Chen, Univ. of California/Irvine (United States)
Brian Jet-Fei Wong, Univ. of California/Irvine (United States)

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