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Journal of Biomedical Optics

Radio frequency electrode system for optical lesion size estimation in functional neurosurgery
Author(s): Johan Antonsson; Ola Eriksson; Karin Wardell
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Paper Abstract

Radiofrequency (RF) lesioning in the human brain is one possible surgical therapy for severe pain as well as movement disorders. One obstacle for a safer lesioning procedure is the lack of size monitoring. The aim of this study was to investigate if changes in laser Doppler or intensity signals could be used as markers for size estimation during experimental RF lesioning. A 2 mm in diameter monopolar RF electrode was equipped with optical fibers and connected to a digital laser Doppler system. The optical RF electrode's performance was equal to a standard RF electrode with the same dimensions. An albumin solution with scatterers was used to evaluate the intensity and laser Doppler signal changes during lesioning at 70, 80, and 90 °C. Significant signal changes were found for these three different clot sizes, represented by the temperatures (p<0.05, n=10). The volume, width, and length of the created coagulations were correlated to the intensity signal changes (r=0.88, n=30, p<0.0001) and to the perfusion signal changes (r=0.81, n=30, p<0.0001). Both static and Doppler-shifted light can be used to follow the lesioning procedure as well as being used for lesion size estimation during experimental RF lesioning.

Paper Details

Date Published: 1 May 2005
PDF: 6 pages
J. Biomed. Opt. 10(3) 034020 doi: 10.1117/1.1924615
Published in: Journal of Biomedical Optics Volume 10, Issue 3
Show Author Affiliations
Johan Antonsson, Linköpings Univ. (Sweden)
Ola Eriksson, Linköpings Univ. (Sweden)
Karin Wardell, Linköpings Univ. (Sweden)

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