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Journal of Biomedical Optics

Infrared analysis of bone in health and disease
Author(s): Adele L. Boskey; Richard Mendelsohn
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Paper Abstract

Infrared spectroscopy, microspectroscopy, and microspectroscopic imaging have been used to probe the composition and physicochemical status of mineral and matrix of bone in normal and diseased tissues using a series of validated parameters that reflect quantitative and qualitative properties. In this review, emphasis is placed on changes in bone's composition and physiochemical status during osteoporosis and the impact of currently used therapeutics on these parameters, although the impact of infrared microscopy in other pathological states is briefly discussed.

Paper Details

Date Published: 1 May 2005
PDF: 9 pages
J. Biomed. Opt. 10(3) 031102 doi: 10.1117/1.1922927
Published in: Journal of Biomedical Optics Volume 10, Issue 3
Show Author Affiliations
Adele L. Boskey, Hospital for Special Surgery (United States)
Richard Mendelsohn, Rutgers Univ. (United States)


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