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Journal of Biomedical Optics

Measurement of brain activity by near-infrared light
Author(s): Enrico Gratton; Vladislav Y. Toronov; Ursula Wolf; Martin Wolf; Andrew G. Webb
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Paper Abstract

We review our most recent results on near-IR studies of human brain activity, which have been evolving in two directions: detection of neuronal signals and measurements of functional hemodynamics. We discuss results obtained so far, describing in detail the techniques we developed for detecting neuronal activity, and presenting results of a study that, as we believe, confirms the feasibility of neuronal signal detection. We review our results on near-IR measurements of cerebral hemodynamics, which are performed simultaneously with functional magnetic resonance imaging (MRI) These results confirm the cerebral origin of hemodynamic signals measured by optical techniques on the surface of the head. We also show how near-IR methods can be used to study the underlying physiology of functional MRI signals.

Paper Details

Date Published: 1 January 2005
PDF: 13 pages
J. Biomed. Opt. 10(1) 011008 doi: 10.1117/1.1854673
Published in: Journal of Biomedical Optics Volume 10, Issue 1
Show Author Affiliations
Enrico Gratton, Univ. of Illinois at Urbana-Champaign (United States)
Vladislav Y. Toronov, Univ. of Illinois at Urbana-Champaign (United States)
Ursula Wolf, Univ. of Illinois at Urbana-Champaign (United States)
Martin Wolf, Univ. of Illinois at Urbana-Champaign (United States)
Andrew G. Webb, Univ. of Illinois at Urbana-Champaign (United States)


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