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Journal of Biomedical Optics

Determination of optical properties in semi-infinite turbid media using imaging measurements of frequency-domain photon migration obtained with an intensified charge-coupled device
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Paper Abstract

Frequency-domain photon migration measurements across the surface of a tissue-mimicking, semi-infinite phantom are acquired via an intensified charge-coupled device (ICCD) detection system and used in conjunction with the diffusion approximation to determine the optical properties. The absorption and reduced scattering coefficients are determined least accurately when relative measurements of average light intensity Irelac are employed either alone or in a combination with relative modulation amplitude data Ireldc and/or relative phase shift data θrel. The absorption and reduced scattering coefficients are found accurate to within 15 and 11%, respectively, of the values obtained from standard single-pixel measurements when rel measurements are employed alone or in combination with Irelac data.

Paper Details

Date Published: 1 November 2004
PDF: 11 pages
J. Biomed. Opt. 9(6) doi: 10.1117/1.1803549
Published in: Journal of Biomedical Optics Volume 9, Issue 6
Show Author Affiliations
Mikhail Gurfinkel, Texas A&M Univ. (United States)
Tianshu Pan, Texas A&M Univ. (United States)
Eva Marie Sevick-Muraca, Texas A&M Univ. (United States)

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