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Journal of Biomedical Optics

Low-intensity indocyanine-green laser phototherapy of acne vulgaris: Pilot study
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Paper Abstract

Near infrared (NIR) diode laser low-intensity (soft) phototherapy with the topical application of indocyanine green (ICG) has been suggested for treatment of acne vulgaris. Twelve volunteers with acne lesions on their faces and/or backs were enrolled in the experiment. Skin areas of the subjects that were 4×5 cm2 were stained with ICG solution for 5 min before laser irradiation (803 nm) at a power density up to 50 mW/cm2 for 5 to 10 min. For 75% of the subjects, a single treatment was provided and for the other 25%, eight sequential treatments over a period of a month were carried out. Observations a month after the completion of the treatment showed that only the multiple treatments with a combination of ICG and NIR irradiation reduced inflammation and improved the state of the skin for a month without any side effects. A month after treatment, the improvement was about 80% for the group receiving multiple treatments. Single treatments did not have a prolonged effect.

Paper Details

Date Published: 1 July 2004
PDF: 7 pages
J. Biomed. Opt. 9(4) doi: 10.1117/1.1756596
Published in: Journal of Biomedical Optics Volume 9, Issue 4
Show Author Affiliations
Elina A. Genina, Saratov State Univ. (Russia)
Alexey N. Bashkatov, Saratov State Univ. (Russia)
Georgy V. Simonenko, Saratov State Univ. (Russia)
Olga D. Odoevskaya, Moscow State Univ. (Russia)
Valery V. Tuchin, Saratov State Univ. (Russia)
Gregory B. Altshuler, Palomar Medical Technologies, Inc. (United States)


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