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Journal of Biomedical Optics

Evaluation of blood plasma coagulation dynamics by speckle analysis
Author(s): Yann Piederriere; Jack Cariou; Yves Guern; Guy Le Brun; Bernard Le Jeune; Jean Lotrian; Jean Francois Abgrall; Maria Therese Blouch
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Paper Abstract

Analysis of speckle dynamics is frequently used to study the motion of scattered objects or liquids. By assessing the increase in contrast on the speckle field produced by a blood plasma sample, illuminated by a laser during a coagulation test, as well as the slowing down of speckle fluctuations, we measured the time required for blood plasma coagulation in vitro and evidence the process dynamics. Then, we compared this noninvasive method with a mechanical viscosity-based detection system classically used in hematology laboratories; our results show good correlation and could provide more information about the blood clotting process.

Paper Details

Date Published: 1 March 2004
PDF: 5 pages
J. Biomed. Opt. 9(2) doi: 10.1117/1.1645799
Published in: Journal of Biomedical Optics Volume 9, Issue 2
Show Author Affiliations
Yann Piederriere, Univ. de Bretagne Occidentale (France)
Jack Cariou, Univ. de Bretagne Occidentale (France)
Yves Guern, Univ. de Bretagne Occidentale (France)
Guy Le Brun, Univ. de Bretagne Occidentale (France)
Bernard Le Jeune, Univ. de Bretagne Occidentale (France)
Jean Lotrian, Univ. de Bretagne Occidentale (France)
Jean Francois Abgrall, Hopital de la Cavale Blanche (France)
Maria Therese Blouch, Hopital de la Cavale Blanche (France)


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