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Journal of Biomedical Optics

Combined multiplanar optical coherence tomography and confocal scanning ophthalmoscopy
Author(s): Adrian Gh. Podoleanu; George M. Dobre; Radu G. Cucu; Richard B. Rosen; Patricia Garcia; Juan Nieto; Daniel V. Will; Ronald C. Gentile; Thomas Muldoon; Joseph B. Walsh; Lawrence A. Yannuzzi; Yale Fisher; Dennis A. Orlock; Rishard Weitz; John Rogers; Shane Dunne; Aaron B. Boxer
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Paper Abstract

We demonstrate the clinical application of a multiplanar imaging system that simultaneously acquires en face (C-scan) optical coherence tomography (OCT) and the corresponding confocal ophthalmoscopic images, along with cross-sectional (B-scan) OCT at specifiable locations on the confocal image. The advantages of the simultaneous OCT and confocal acquisition as well as the challenges of interpreting the C-scan OCT images are discussed. Variations in tissue inclination with respect to the coherence wave surface alter the sampling of structures within the depth of the retina, producing novel slice orientations that are often challenging to interpret. We have evaluated for the first time the utility of C-scan OCT for a variety of pathologies, including melanocytoma, diabetic retinopathy, choroidal neovascular membrane, and macular pucker. Several remarkable new aspects of clinical anatomy were revealed using this new technique. The versatility of selective capture of C-scan OCT images and B-scan OCT images at precise points on the confocal image affords the clinician a more complete and interactive tool for 3-D imaging of retinal pathology.

Paper Details

Date Published: 1 January 2004
PDF: 8 pages
J. Biomed. Opt. 9(1) doi: 10.1117/1.1627778
Published in: Journal of Biomedical Optics Volume 9, Issue 1
Show Author Affiliations
Adrian Gh. Podoleanu, Univ. of Kent at Canterbury (United Kingdom)
George M. Dobre, Univ. of Kent at Canterbury (United Kingdom)
Radu G. Cucu, Univ. of Kent at Canterbury (United Kingdom)
Richard B. Rosen, New York Eye and Ear Infirmary (United States)
Patricia Garcia, New York Eye and Ear Infirmary (United States)
Juan Nieto, New York Eye and Ear Infirmary (United States)
Daniel V. Will, CUNY/City College (United States)
Ronald C. Gentile, New York Eye and Ear Infirmary (United States)
Thomas Muldoon, New York Eye and Ear Infirmary (United States)
Joseph B. Walsh, New York Eye and Ear Infirmary (United States)
Lawrence A. Yannuzzi, LuEsther T. Mertz Retinal Research Ctr. (United States)
Yale Fisher, LuEsther T. Mertz Retinal Research Ctr. (United States)
Dennis A. Orlock, LuEsther T. Mertz Retinal Research Ctr. (United States)
Rishard Weitz, Ophthalmic Technology Inc. (Canada)
John Rogers, Ophthalmic Technologies Inc. (Canada)
Shane Dunne, Ophthalmic Technologies Inc. (Canada)
Aaron B. Boxer, Ophthalmic Technologies Inc. (Canada)


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