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Journal of Biomedical Optics

Calculation of ocular single-pass modulation transfer function and retinal image simulation from measurements of the polarized double-pass ocular point spread function
Author(s): Katsuhiko Kobayashi; Masahiro Shibutani; Gaku Takeuchi; Kazuhiko Ohnuma; Yoichi Miyake; Kazuno Negishi; Kenji Ohno; Tohru Noda
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Paper Abstract

The single-pass modulation transfer function (MTFsgl) is an important numerical parameter that can help elucidate the performance and some processes of the human visual system. In previous studies, the MTFsgl was calculated from double-pass point spread function (PSF) measurements. These measurements include a depolarized reflection component from the retina that introduces a measurement artifact, and they require long acquisition times to allow averaging to reduce speckle. To solve these problems, we developed a new ocular PSF analysis system (PSFAS) that uses polarization optics to eliminate the depolarized retinal reflection component, and a rotating prism to increase measurement speed. Validation experiments on one patient showed that the MTFsgl measured by PSFAS agrees closely with the MTF calculated from contrast sensitivity measurements. A simulated retinal image was calculated by convolution of Landolt rings with the calculated single-pass PSF provided by the PSFAS. The contrast characteristic then was calculated from the simulated retinal images. These results indicate that the MTFsgl obtained using the PSFAS may be a reliable measure of visual performance of the optics of the eye, including the optical effects of the retina. The simulated retinal images and contrast characteristics are useful for evaluating visual performance.

Paper Details

Date Published: 1 January 2004
PDF: 8 pages
J. Biomed. Opt. 9(1) doi: 10.1117/1.1627777
Published in: Journal of Biomedical Optics Volume 9, Issue 1
Show Author Affiliations
Katsuhiko Kobayashi, Topcon Corp. (Japan)
Masahiro Shibutani, Topcon Corp. (Japan)
Gaku Takeuchi, Topcon Corp. (Japan)
Kazuhiko Ohnuma, Chiba Univ. (Japan)
Yoichi Miyake, Chiba Univ. (Japan)
Kazuno Negishi, Keio Univ. (Japan)
Kenji Ohno, National Tokyo Medical Ctr. (Japan)
Tohru Noda, National Tokyo Medical Ctr. (Japan)

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