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Journal of Biomedical Optics

New optical scheme for a polarimetric-based glucose sensor
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Paper Abstract

A new optical scheme to detect glucose concentration in the aqueous humor of the eye is presented. The ultimate aim is to apply this technique in designing a new instrument for, routinely and frequently, noninvasively monitoring blood glucose levels in diabetic patients without contact (no index matching) between the eye and the instrument. The optical scheme exploits the Brewster reflection of circularly polarized light off of the lens of the eye. Theoretically, this reflected linearly polarized light on its way to the detector is expected to rotate its state of polarization, owing to the presence of glucose molecules in the aqueous humor of a patient's eye. An experimental laboratory setup based on this scheme was designed and tested by measuring a range of known concentrations of glucose solutions dissolved in water.

Paper Details

Date Published: 1 January 2004
PDF: 13 pages
J. Biomed. Opt. 9(1) doi: 10.1117/1.1626664
Published in: Journal of Biomedical Optics Volume 9, Issue 1
Show Author Affiliations
Rafat R. Ansari, NASA Glenn Research Ctr. (United States)
Stefan Boeckle, NASA Glenn Research Ctr. (Italy)
Luigi L. Rovati, Univ. degli Studi di Modena e Reggio Emilia (Italy)

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