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Journal of Biomedical Optics

Subsurface skin renewal by treatment with a 1450-nm laser in combination with dynamic cooling
Author(s): Dilip Y. Paithankar; Joan M. Clifford; Bilal A. Saleh; E. Victor Ross; Christina A. Hardaway; David Barnette
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Paper Abstract

A new nonablative laser device, Smoothbeam, has been under evaluation for nonablative wrinkle reduction in skin with minimal side effects. This device incorporates a laser at 1450-nm wavelength to heat the dermis and cryogen spray cooling to prevent epidermal damage. The thermal injury created is internal and imperceptible. The wound-healing response to this internal injury causes improvement in the appearance of skin wrinkles. Biopsies taken immediately after treatment showed mild residual thermal damage (RTD) at a depth range of 150 to 400 μm, which is the dermal zone where most solar elastosis resides. Biopsies from two months after treatment showed fibroplasia extending over a range of depths similar to the acute RTD zones. An improvement in wrinkle severity was noted on the treated side compared with the control side.

Paper Details

Date Published: 1 July 2003
PDF: 7 pages
J. Biomed. Opt. 8(3) doi: 10.1117/1.1586703
Published in: Journal of Biomedical Optics Volume 8, Issue 3
Show Author Affiliations
Dilip Y. Paithankar, Candela Corp. (United States)
Joan M. Clifford, Candela Corp. (United States)
Bilal A. Saleh, Candela Laser Corp. (United States)
E. Victor Ross, San Diego Naval Medical Ctr. (United States)
Christina A. Hardaway, Naval Medical Ctr. (United States)
David Barnette, Naval Medical Ctr. (United States)

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