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Journal of Biomedical Optics

Optoacoustic determination of optical attenuation depth using interferometric detection
Author(s): Barry P. Payne; Vasan Venugopalan; Bora B. Mikic; Norman S. Nishioka
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Paper Abstract

We use a modified Mach-Zehnder interferometer to measure surface displacement resulting from the thermoelastic response of a target to the absorption of a short laser pulse with axial and temporal resolutions of 0.1 nm and 3 ns, respectively. These measurements are used in conjunction with a solution to the thermoelastic wave equation and a nonlinear optimization algorithm to extract optical attenuation depth. We demonstrate the ability to determine the effective optical attenuation depth of homogeneous targets with either diffuse or specular reflecting surfaces with a precision of 4% for attenuation depths spanning 0.1 to 2 mm.

Paper Details

Date Published: 1 April 2003
PDF: 9 pages
J. Biomed. Opt. 8(2) doi: 10.1117/1.1559731
Published in: Journal of Biomedical Optics Volume 8, Issue 2
Show Author Affiliations
Barry P. Payne, Massachusetts Institute of Technology (United States)
Vasan Venugopalan, Univ. of California/Irvine (United States)
Bora B. Mikic, Massachusetts Institute of Technology (United States)
Norman S. Nishioka, Massachusetts General Hospital (United States)

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