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Journal of Biomedical Optics

Effect of temperature, pH, and corneal birefringence on polarimetric glucose monitoring in the eye
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Paper Abstract

Over the last two decades polarimetry has been investigated as a noninvasive alternative for glucose monitoring in support of diabetic patients. In particular, the anterior chamber of the eye containing the fluid known as the aqueous humor has been confirmed to be the optimal sensing site for polarimetric glucose measurements due to its reasonable pathlength (1 cm), low scatter, and minimal depolarization index. In essence, the eye can be thought of as an optical window into the body. In this paper, we will first introduce the key challenges that must be overcome to make the use of polarized light in the eye a viable method for noninvasive glucose monitoring, summarize our work toward this endeavor, and then report on our latest research, namely, the effect of temperature, pH , and corneal birefringence on our polarimetric glucose monitoring system.

Paper Details

Date Published: 1 July 2002
PDF: 8 pages
J. Biomed. Opt. 7(3) doi: 10.1117/1.1484163
Published in: Journal of Biomedical Optics Volume 7, Issue 3
Show Author Affiliations
Justin S. Baba, Texas A&M Univ. (United States)
Brent D. Cameron, Univ. of Toledo and Texas A&M Univ. (United States)
Gerard L. Cote, Texas A&M Univ. (United States)

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