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Journal of Biomedical Optics

Photon pathlength determination based on spatially resolved diffuse reflectance
Author(s): Henrik Nilsson; Marcus Larsson; Gert E. Nilsson; Tomas Stroemberg
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Paper Abstract

A method for the prediction of the average photon pathlength in turbid media has been developed. The method is based on spatially resolved diffuse reflectance with discrete source detector distances up to 2 mm. Light reflectance was simulated using a Monte Carlo technique with a one-layer model utilizing a wide range of optical properties, relevant to human skin. At a source detector separation of 2 mm, the pathlength can vary sixfold due to differences in optical properties. By applying various preprocessing and prediction techniques, the pathlength can be predicted with a root-mean-square error of approximately 5%. Estimation of the photon pathlength can be used, e.g., to remove the influence of optical properties on laser Doppler flowmetry perfusion readings, which are almost linearly related to the average photon pathlength.

Paper Details

Date Published: 1 July 2002
PDF: 8 pages
J. Biomed. Opt. 7(3) doi: 10.1117/1.1482378
Published in: Journal of Biomedical Optics Volume 7, Issue 3
Show Author Affiliations
Henrik Nilsson, Linkoeping Univ. (Sweden)
Marcus Larsson, Linkoeping Univ. (Sweden)
Gert E. Nilsson, Linkoeping Univ. (Sweden)
Tomas Stroemberg, Linkoeping Univ. (Sweden)


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